Anti-tumor compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514260, 544284, 544285, 544287, C07D23996, C07D23995, C07D23990, A61K 31505

Patent

active

052800270

ABSTRACT:
The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them.
The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 includes hydrogen, amino and alkyl or alkoxy each of up to 4 carbon atoms;

REFERENCES:
patent: 4447608 (1984-05-01), Jones et al.
patent: 4857530 (1989-08-01), Berman et al.
patent: 4981856 (1991-01-01), Hughes
patent: 4985441 (1991-01-01), Hughes et al.
patent: 4992550 (1991-02-01), Hughes
Fessenden et al. "Organic Chemistry" 2nd Ed. pp. 714-721 (1982) Willard Press.

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