Anti-tumor composition

Details Anti-tumor composition Anti-tumor composition

2011-07-05

2011-07-05

Anderson, James D (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

C514S548000, C514S646000, C514S720000

Reexamination Certificate

active

07973076

ABSTRACT:
The present invention provides compositions having, as active ingredients, a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.

REFERENCES:
patent: 4140707 (1979-02-01), Cleare et al.
patent: 4935450 (1990-06-01), Cone, Jr.
patent: 5525632 (1996-06-01), Obsumi et al.
patent: 5674906 (1997-10-01), Hatanaka et al.
patent: 5700826 (1997-12-01), Mjalli et al.
patent: 5728687 (1998-03-01), Bissery
patent: 5731353 (1998-03-01), Obsumi et al.
patent: 5844001 (1998-12-01), McClay et al.
patent: 6462087 (2002-10-01), Morinaga et al.
patent: 2002/0193434 (2002-12-01), Morinaga et al.
patent: 2004/0192621 (2004-09-01), Nihei et al.
patent: 0 276 051 (1988-07-01), None
patent: 0 641 767 (1995-03-01), None
patent: 7-228558 (1995-08-01), None
patent: 8-301831 (1996-11-01), None
patent: WO 91/04058 (1991-04-01), None
patent: WO 92/16486 (1992-10-01), None
patent: WO 95/00129 (1995-01-01), None
patent: WO 95/20960 (1995-08-01), None
patent: WO 97/08184 (1997-03-01), None
patent: WO 98/33481 (1998-08-01), None
patent: WO 00/09097 (2000-02-01), None
patent: WO 00/48590 (2000-08-01), None
patent: WO 01/12579 (2001-02-01), None
patent: WO 02/056692 (2002-07-01), None
patent: WO 02/074229 (2002-09-01), None
“Baylor, St. Luke's study uses gene therapy as pancreatic cancer”, April Sutton, www.bcm.edu, 2006.
“Drugs hold promise in kidney cancer fight”, Marchione et al., www.ledger-enquireer.com, 2006.
Cecil Textbook of Medicine 20thEdition, 1997.
Gatzemeier et al. Seminars in Oncology, 1990, vol. 17, No. 1, suppl. 2, pp. 25-31 (Abstract attached).
Greco et al. Seminars in Oncology, 1996, vol. 23, No. 6, suppl. 16, pp. 7-10 (Abstract attached).
Paccagnella et al. Cancer, 1996, vol. 78, No. 8, pp. 1701-1707 (Abstract attached).
Belani et al. Oncology, 1997, vol. 11, No. 8, suppl. 8, pp. 42-45 (Abstract attached).
U.S. Appl. No. 12/622,508, filed Nov. 20, 2009, Morinaga, et al.
“Enhancing and Inhibitory Effects of Some Stilbene and Steroid Compounds on Induction of Hepatoma in Rats Fed 3'-Methyl-4-(Dimethylamino)Azobenzene”, Gann, 69, No. 3, pp. 375-382, Jun. 1978 (Chiba).
Anti-Leukaemic Compounds Derived From Stilbenes in Picea Abies Bark:, Phytochemistry, vol. 33, No. 4, 1993, pp. 813-816.
Tashiro, Nippon Kagaku Kaishi (1988), 684-90 Abstract Only.
American Association for Cancer Research, Eighty-Ninth Annual Meeting, Proceedings, Mar. 28-Apr. 1, 1998, New Orleans, LA., vol. 39—Mar. 1998.
B. Nakata, et al., Cancer Chemotherapy and Pharmacology, vol. 35, No. 6, pp. 511-518, XP-008010359, “Synergistic Interaction Between Cisplatin and Tamoxifen Delays the Emergence of Cisplatin Resistance in Head and Neck Cancer Cell Lines”, 1995.
E.F. McClay, et al., “British Journal of Cancer, vol. 70, No. 3, pp. 449-452, XP-008010360, ”Tamoxifen Delays the Development of Resistance to Cisplatin in Human Melanoma and Ovarian Cancer Cell Lines, 1994.
Patent Abstracts of Japan, JP 56-103192, Aug. 18, 1981.
M. Cushman, et al., Journal of Medicinial Chemistry, vol. 34, No. 8, pp. 2579-2588, XP-000571676, “Synthesis and Evaluation of Stilbene and Dihydrostilbene Derivatives As Potential Anticancer Agents That Inhibit Tubulin Polymerization”, 1991.
J.A. Woods, et al., British Journal of Cancer, vol. 71, No. 4, pp. 705-711, XP-000978556, “The Interaction With Tubulin of a Series of Stilbenes Based on Combretastatin A-4”, 1995.
Yoshihiro Morinaga, et al., “Combination effect of AC-7700, a novel combretastatin A-4 derivative, and cisplatin against murine and human tumors in vivo” Cancer Sci., Feb. 2003, vol. 94, No. 2, pp. 200-204.

Affiliated with

Also associated with

Rating

Anti-tumor composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-tumor composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-tumor composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2665937