Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-11-18
1993-10-12
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514260, 544284, 544285, 544287, C07D23996, C07D23972, A61K 31505, A01N 4354
Patent
active
052525732
ABSTRACT:
The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them.
The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R.sup.1 is substituted alkyl or alkoxy each of up to 3 carbon atoms;
REFERENCES:
patent: 4447608 (1984-05-01), Jones et al.
patent: 4857530 (1989-08-01), Berman et al.
patent: 4981856 (1991-01-01), Hughes
patent: 4992550 (1991-02-01), Hughes
Barker Andrew J.
Hughes Leslie R.
Marsham Peter R.
Oldfield John
Pegg Stephen J.
Grumbling Matthew V.
Imperial Chemical Industries plc
National Research Development Corporation
Shah Mukund J.
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