Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-04-03
1991-01-15
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514259, 544284, 544285, 544207, A61K 31505, C07D23990
Patent
active
049854410
ABSTRACT:
The invention relates to quinazoline derivatives which possess anti-tumor activity; to processes for their manufacture; and to pharmaceutical compositions containing them.
The invention provides a quinazoline of the formula: ##STR1## wherein R.sup.1 is hydrogen or amino, or alkyl or alkoxy each of up to 6 carbon atoms; or R.sup.1 is substituted alkyl or alkoxy each of up to 3 carbon atoms;
REFERENCES:
patent: 4447608 (1984-05-01), Jones et al.
Hughes, "Chemical Abstracts", vol. 108, 1988, Col. 108:205094d.
Jones et al., "Chemical Abstracts," vol. 110, 1989, Col. 110:173724g.
Patil et al., "Chemical Abstracts", vol. 110, 1989, Col. 110:232041g.
Hughes Leslie R.
Oldfield John
Pegg Stephen J.
Hollrah Glennon H.
Imperial Chemical Industries plc
National Research Development Corp.
Turnipseed James H.
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