Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1993-10-25
1997-09-23
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
435 4, 435 6, C12Q 148
Patent
active
056703309
ABSTRACT:
A method of screening human tissue for the presence of neoplastic cells, by determining the activity of PKR, P58 of anti-P58 in test cells being screened, and identifying candidate neoplastic cells on the basis of subnormal PKR, P58, or anti-P58 activity. The activities may be determined directly by measuring protein kinase activity or its equivalent, or measured indirectly, by detecting functional mutations in the various proteins. Also disclosed are assay kits for carrying out the screening method.
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Barber Glen H.
Katze Michael G.
Koromilas Antonis E.
Roy Sophie
Sonenberg Nahum
Lau Kawai
McGill University
University of Washington
Wax Robert A.
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