Anti tubercular drug: compositions and methods

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S306000, C514S317000, C514S649000, C514S653000, C514S654000, C514S655000, C514S659000, C514S660000, C564S316000, C564S320000, C564S355000, C564S366000, C564S368000, C564S369000, C564S370000, C564S453000, C564S454000, C564S455000, C564S457000, C546S134000, C546S194000, C546S246000

Reexamination Certificate

active

07456222

ABSTRACT:
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.

REFERENCES:
patent: 2623878 (1952-12-01), Isler et al.
patent: 3176040 (1965-03-01), Wilkinson et al.
patent: 3553257 (1971-01-01), Halmos et al.
patent: 3579586 (1971-05-01), Zoja
patent: 3579587 (1971-05-01), Zoja
patent: 3718655 (1973-02-01), Ferrer-Salat et al.
patent: 3769347 (1973-10-01), Kazan
patent: 3829493 (1974-08-01), Butula et al.
patent: 3847991 (1974-11-01), Bernardi et al.
patent: 3855300 (1974-12-01), Takahashi et al.
patent: 3878201 (1975-04-01), Tomcufcik
patent: 3931152 (1976-01-01), Tomcufcik et al.
patent: 3931157 (1976-01-01), Child et al.
patent: 3944608 (1976-03-01), Singh
patent: 3944616 (1976-03-01), Kazan
patent: 3944617 (1976-03-01), Singh
patent: 3944618 (1976-03-01), Singh
patent: 3944619 (1976-03-01), Singh
patent: 3953513 (1976-04-01), Oppici
patent: 3979457 (1976-09-01), Fujii et al.
patent: 4006234 (1977-02-01), Child et al.
patent: RE29358 (1977-08-01), Tomcufcik
patent: RE29588 (1978-03-01), Halmos et al.
patent: 4150030 (1979-04-01), Singh
patent: 4262122 (1981-04-01), Lees et al.
patent: 4450274 (1984-05-01), Park
patent: 5104875 (1992-04-01), Jurgen et al.
patent: 5439891 (1995-08-01), Kapil et al.
patent: 5922282 (1999-07-01), Ledley
patent: 5985935 (1999-11-01), Kharazmi et al.
patent: 2003/0236225 (2003-12-01), Protopopova et al.
patent: 2004/0033986 (2004-02-01), Protopopova et al.
patent: 2007524 (1969-04-01), None
patent: 729332 (1955-05-01), None
patent: 961317 (1964-06-01), None
patent: 1234349 (1971-06-01), None
patent: 2168986 (2001-06-01), None
patent: WO 99/51213 (1999-10-01), None
Database CAPLUS on STN, Acc. No. 1973:38547, Hamilton-Miller, Chemotherapy (1973), 18(3), p. 154-61 (abstract).
Database CAPLUS on STN, Acc. No. 2003:49639, Lee et al., Journal of Combinational Chemistry (2003), 5(2), p. 172-187 (abstract).
Author: Arain, T. et al., Title: Bioluminescence Screening in Vitro (Bio-Siv) Assays for High-Volume Antimycobacterial Drug Discovery, Publ:Antimicrobial Agents and Chemotherapy, vol./Iss: 40(6), pp. 1536-1541, Date: Jan. 1, 1996.
Author: Barry, C. et al., Title: Use of Genomics and Combinatorial Chemistry in the Development of New Antimycobacterial Drugs, Publ:Biochemical Pharmacology, vol./Iss: 59, pp. 221-231, Date: Jan. 1, 2000.
Author: Bass, J. et al., Title: Treatment of Tuberculosis and Tuberculosis Infection in Adults and Children, Publ:American Journal of Resiratory and Critical Care Medicine, vol./Iss: 149, pp.1359-1374, Date: Jan. 1, 1994.
Author: Belanger, A et al., Title: The EmbAB Genes of Mycobacterium Avium Encode an Arabinosyl Transferase Involved in Cell Wall Arabinan Biosynthesis that is the Target for the Antimycobacterial Drug Ethambutol, Publ:Proceedings of the National Academy of Science, vol./Iss. 93, pp. 11919-11924, Date: Jan. 1, 1996.
Author: Brown, D. et al. Title: Merrified Alpha-Methoxyphenyl (MAMP) Resin: A New Versatile Solid Support for the Synthesis of Secondary Amines, Publ:Tetrahedron Letters, vol./Iss. 39, pp. 8533-8536, Date: Jan. 1, 1998.
Chan-Tack, K., Title: Antituberculosis-Drug Resistance, Publ:New England Journal of Medicine, vol./Iss. 339(15), pp. 1079, Date: Jan. 1, 1998.
Author: Cole, S. et al., Title: Deciphering the Biology of Mycobacterium Tuberculosis from the Complete Genome Sequence, Publ:Nature, vol./Iss: 393, pp. 537-544, Date: Jan. 1, 1998.
Author: Cuervo, J. et al., Title: Polyalkylamine Chemical Combinatorial Libraries, Publ:Peptides 1994: Proceedings of the European Peptide Symposium, pp. 465-466, Date: Jan. 1, 1995.
Author: Cymerman-Craig, J. et al., Title: Chemical Constitution and Anti-Tuberculous Activity: Part II: Bases Possessing the Diphenyl Structure, Publ:British Journal of Experimental Pathology, vol./Iss: 36, pp. 254-260, Date: Jan. 1, 1955.
Author: Cynamon et al., Title: Activities of Several Novel Oxazolidinones Against Mycobacterium Tuberculosis in a Murine Model, Publ:Antimicrobial Agents and Chemotherapy, vol./Iss: 43(5), pp. 1189-1191, Date: May 1, 1999.
Author: Deng, I. et al., Title: Recognition of Multiple Effects of Ethambutol on Metabolism of Mycobacterial Cell Envelope, Publ:Antimicrobial Agents and Chemotherapy, vol./Iss: 39(3), pp. 694-701, Date: Jan. 1, 1995.
Author: Dye, C. et al., Title: Global Burden of Tuberculosis: Estimated Incidence, Prevalence and Mortality by Country, Publ:Journal of the American Medical Association, vol./Iss: 282(7), pp. 677-686, Date: Jan. 1, 1999.
Author: Farmer, P. et al., Title: The Dilemma of MDR-TB in the Global Era, Publ:International Journal of Tuberculosis and Lung Disease, vol./Iss: 2(11), pp. 869-876, Date: Jan. 1, 1998.
Author: Garigipati, R., Title: Reagents for Combinatorial Organic Synthesis: Preparation and Uses of Rink-Chloride, Publ:Tetrahedron Letters, vol./Iss: 38(39), pp. 6807-6810, Date: Jan. 1, 1997.
Author: Gordon, D., Title: Reductive Alkylation on a Solid Phase: Synthesis of Piperazinedione Combinatorial Library, Publ:Bioorganic&Medicinal Chemistry Letters, vol./Iss: 5(1), pp. 47-50, Date: Jan. 1, 1995.
Author: Gustafson, G., Title: Incorporation of Carbohydrates and Peptides into Large Triazine-Based Screening Libraries Using Automated Parallel Synthesis, Publ:Tetrahedron, vol./Iss: 54, pp. 4051-4065, Date: Jan. 1, 1998.
Author: Hamilton-Miller, J.M., Title: Inhibition ofCandidaby Compounds which Inhibit Cholesterol Biosynthesis, Publ:Chemotherapy, vol./Iss: 18, pp. 154-161, Date: Jan. 1, 1973.
Author: Hausler, H. et al., Title: Ethambutol Analogues as Potential Antimycobacterial Agents, Publ:Bioorganic&Medicinal Chemistry Letters, vol./Iss: 11, pp. 1678-1681, Date: Jan. 1, 2001.
Author: Lee, M. et al., Title: Site-Specific Integration of Mycobacteriophage L5: Integration-Proficient Vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacilli Calmette-Guerin, Publ:Proceedings of the National Academy of Science, vol./Iss: 88, pp. 3111-3115, Date: Jan. 1, 1991.
Author: Lee, R., Title: Combinatorial Lead Optimization of [1,2]-Diamines Based on Ethambutol as Potential Antituberculosis Preclinical Candidates, Publ:Journal of Combinatorial Chemistry, vol./Iss: 5, pp. 172-187, Date: Jan. 1, 2003.
Author: Lee, R. et al., Title: Synthesis of the Mycobacterial Arabinose Donor β-D-Arabinofuranosyl-1-monophosphoryldecaprenol, Development of a Basic Arabinosyl-Transferase Assay, and Identification of Ethambutol as an Arabinosyl Transferase Inhibitor, Publ:Journal of the American Chemical Society, vol./Iss: 117, pp. 11829-11832, Date: Jan. 1, 1995.
Author: Liu, G. et al., Title: A General Solid-Phase Syntheses Strategy for the Preparation of 2-Pyrrolidinemethanol Ligands, Publ:Journal of Organic Chemistry, vol./Iss: 60, pp. 7712-7713, Date: Jan. 1, 1995.
Author: March, J., Title: Advanced Organic Chemistry: Reactions, Mechanisms and Structure, 3rd edition; Publisher: John Wiley and Sons, New York, pp. 916, Date: Jan. 1, 1985.
Author: O'Brien, R., Title: Scientific Blueprint for Tuberculosis Drug Development; Publisher: the Global Alliance for TB Drug Development, Inc., Date: Jan. 1, 2001.
Author: Pablos-Mendez, A. et al., Title: Global Surveillance for Antituberculosis Drug Resistance 1994-1997, Publ:New England Journal of Medicine, vol./Iss: 338(23), pp. 1641-1649, Date: Jan. 1, 1998.
Author: Rink, H., Title: Solid-Phase Synthesis of Protected Peptide Fragments Using a Trialkoxy-Diphenyl-Methylester Resin, Publ:Tetrahedron Letters, vol./Iss: 28(33), pp. 3787-3790, Date: Jan. 1, 1987.
Author: Roark, W. et al., Title: Bioisosterism in Drug Design: Identification of and Structure-Activity Relationships in a Series of Glycine Anilide ACAT Inhibitors, Publ:Bioorganic&Medicinal Chemistry Letters, vol./Iss: 3 (1), pp. 29-39, Date: Jan. 1, 1995.
Author: S/ Budavari, ed., Publ:t

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti tubercular drug: compositions and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti tubercular drug: compositions and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti tubercular drug: compositions and methods will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4028138

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.