Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated to proteinaceous toxin or fragment thereof
Patent
1982-05-12
1984-03-20
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated to proteinaceous toxin or fragment thereof
424180, 536 21, 536 551, 536 552, 536123, A61K 3514, C08B 3710
Patent
active
044381085
ABSTRACT:
A new anti-thromboticum based on a mixture of oligo- and polysaccharides is provided. The invention also relates to methods for preparation thereof and to pharmaceutical compositions including the said anti-thromboticum.
The new product is of natural origin and can be obtained from mammal tissue, particularly intestinal mucous. The product is useful because of its high "benefit/risk" ratio (i.e. the ratio between the anti-thrombotic activity and the haemorrhagic activity).
REFERENCES:
patent: 4175182 (1979-11-01), Schmer
patent: 4301028 (1981-11-01), Bartl et al.
patent: 4301153 (1981-11-01), Rosenberg
patent: 4303651 (1981-12-01), Lindahl et al.
patent: 4351938 (1982-09-01), Barnett
Meuleman Dirk G.
Moelker Huibert C. T.
Sanders Adrianus L. M.
Van Dedem Gijsbert W. K.
Van Houdenhoven Francois E. A.
Akzo N.V.
Brown Johnnie R.
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