Anti TfR antibody

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S387100, C530S387300, C536S023400, C536S023530

Reexamination Certificate

active

07976841

ABSTRACT:
The invention relates to the monoclonal antibody A24 directed against the transferrin receptor. This antibody is in particular useful as an antiproliferative agent.

REFERENCES:
patent: 5530101 (1996-06-01), Queen et al.
patent: 5667781 (1997-09-01), Trowbridge et al.
Taetle et al. (Can. Res. 46: 1759-1763 (1986)).
Trowbridge and Lopez (Proc. Natl Acad Sci USA, 79, 1175-1179, 1982).
Taetle et al. (Cancer Res., 46, 1759-1763, 1986).
White et al. (Cancer Res., 50, 6295-301, 1990).
Lesley et al. (Mol Cell Biol. 5, 1814-21, 1985).
MacCallum et al. (J. Mol. Biol. (1996) 262:732-745).
De Pascalis et al. The Journal of Immunology (2002) 169, 3076-3084.
Casset et al. (2003) BBRC 307, 198-205.
Vajdos et al. (2002) J. Mol. Biol. 320, 415-428.
Holm et al (2007) Mol. Immunol. 44: 1075-1084.
Chen et al. J. Mol. Bio. (1999) 293, 865-881.
Wu et al. J. Mol. Biol. (1999) 294, 151-162.
Fujimori et al. (J. Nuc. Med. 31:1191-1198 (1990)).
Beckman et al. (Can. 109:170-179 (2007)).
Thurber et al. (Adv. Drug Deliv. Rev. 60:1421-1434 (2008)).
Rudnick et al. (Can. Biotherp. & Radiopharm. 24: 155-162 (2009)).
Moura, I.C., et al., “Identification of the Transferrin Receptor as a Novel Immunoglobulin (Ig)A1 Receptor and its Enhanced Expression on Mesangial Cells in IgA Nephropathy,” Journal of Experimental Medicine, Tokyo, JP, Aug. 20, 2001, vol. 194, No. 4, pp. 417-425, XP002273386, ISSN: 0022-1007, cited in the application, the whole document.
Moura, Ivan C., et al., “A Neutralizing Monoclonal Antibody (mAb A24) Directed Against the Transferrin Receptor Induces Apoptosis of Tumor T Lymphocytes from ATL Patients,” Blood, Mar. 1, 2004, vol. 103, No. 5, pp. 1838-1845, XP002313955, ISSN: 0006-4971, the whole document.
Written Opinion of the International Searching Authority (“ISA”).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti TfR antibody does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti TfR antibody, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti TfR antibody will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2631522

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.