Anti-streptolysin O latex reagent and process for the preparatio

Details Anti-streptolysin O latex reagent and process for the preparatio Anti-streptolysin O latex reagent and process for the preparatio

1983-03-17

1985-04-02

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving antibody fragments

435 7, 436533, 436534, 436811, 436815, G01N 3354

Patent

active

045088314

ABSTRACT:
A process for the preparation of an antistreptolysin O latex reagent and the reagent produced by such process. The reagent is prepared by reacting streptolysin O with a bifunctional low molecular weight compound and, in the preferred embodiment, with a gamma globulin or a Fab fragment thereof to form a product, which product is adsorbed to latex particles. The reagent is stable and may be used for the determination of antibodies to streptolysin O.

REFERENCES:
patent: 3992631 (1976-11-01), Harte
patent: 4088749 (1978-05-01), Grundman
patent: 4148609 (1979-04-01), Ricci
patent: 4329151 (1982-05-01), Lou
Chemical Abstracts, 73: 1975r (1970).

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