Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Reexamination Certificate
2001-10-24
2002-12-10
Lilling, Herbert J. (Department: 1651)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
C424S725000, C424S726000, C424S769000, C424S776000, C424S779000
Reexamination Certificate
active
06491954
ABSTRACT:
BACKGROUND OF THE INVENTION
Snoring is a sleep disorder that can range from mild to severe in humans. Mild cases may result in no more than fitful sleep by the sufferer, while severe cases at the minimum cause disturbance of the sleep of others, and may result in insufficient inhalation of oxygen by the sufferer, apnea and, in extreme cases, death.
Many attempts have been made to devise remedies to alleviate the symptoms of snoring, ranging from surgery to a variety of medicaments. Although surgery has been proven to be somewhat effective, it is a radical and expensive approach that is subject to all the usual risks associated with surgery. There are a few effective drugs available for the treatment of the symptoms of snoring, but these are typically available only by way of prescription. There is therefore a need for an inexpensive non-prescription anti-snoring composition that is safe and effective. This need is fulfilled by the present invention, which is summarized and described in detail below.
BRIEF SUMMARY OF THE INVENTION
The invention comprises an anti-snoring composition made up of an aqueous ethanolic solution of seven active homeopathic ingredients, namely (i) Belladonna, (ii)
Ephedra vulgaris
, (iii)
Histamine hydrochloride
, (iv)
Hydrastis canadensis
, (v)
Potassium dichromate
, (vi)
Nux vomica
and (vii)
Teucrim marum.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
According to the present invention the composition is made by combining equal parts by weight of eight aqueous ethanolic solutions of the aforementioned seven active homeopathic ingredients. Each ingredient is diluted in accordance with conventional homeopathic formulation procedures using an aqueous solution containing 20 vol % of 95 vol % ethanol.
Active ingredients (iii) (
Histamine hydrochloride
) and (v) (
Potassium dichromate
) are organic and inorganic chemicals, respectively, and are commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel, Inc. of Santa Rosa, Calif. The remainder of the active ingredients are all derived from plants as follows: (i) Belladonna—an alkaloid extracted from the entire plant from roots to flower of Deadly Nightshade plant, commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel; (ii)
Ephedra vulgaris—
a decongestant extracted from the stems and branches of the Ma huang or Mormon tea plant, commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel; (iv)
Hydrastis canadensis—
the active ingredient comprises three isoquinoline alkaloids extracted from the air-dried rhizome and roots of the herb Golden seal, commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel; (vi)
Nux vomica—
the active ingredient extracted from coarsely powdered seeds of the Poison nut or Quaker buttons plant, commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel; and (vii)
Teucrim marum—
the active ingredient extracted from the entire plant Cat thyme, commercially available in 20 vol % aqueous ethanolic solutions from Boericke & Tafel.
In a preferred formulation, most of the active ingredients are diluted 6× in accordance with the standard homeopathic dilution procedures, with one of the ingredients being diluted 12× and one diluted both 4× and 6×. By “standard homeopathic dilution procedures” is meant that a dilution of 1=1 part by weight active to 9 parts by weight diluent or, in other words, a 10 wt % solution; a 2× dilution=1 part by weight of a 1× solution to 9 parts by weight of diluent dilution, or a 1 wt % solution; a 3× dilution=1 part by weight of a 2× solution to 9 parts by weight of diluent, or a 0.1 wt % solution; and so on. All dilutions may vary with a tolerance of ±10%, preferably ±2%.
Ingredients (i)-(ii) and (iv)-(vii) are preferably diluted 6×, while ingredient (iii) is preferably diluted 12×. In addition to the 6× dilution, ingredient (vi) is also preferably diluted 4×. The solutions of actives may form from about 75 to about 95 wt % of the composition, preferably about 90 wt %. A carrier liquid such as glycerin or other compatible adjuvant may be included in the composition from about 5 to about 15 wt %, preferably about 10 wt %. A preservative may be present in a relatively small amount, say from about 0.05 to about 1 wt %, preferably 0.1 wt %; a preferred preservative is potassium sorbate.
While the composition may be formulated into a wide variety of administration forms such as drops or sprays, the most preferred form is throat spray, as this form has been shown to be effective at quick adsorption into the bloodstream through the mucous membranes of the mouth and throat passageways. The following example demonstrates how to formulate an exemplary embodiment of the invention.
REFERENCES:
“PDR for Herbal Medicines” “Ephedra Sinica”; “Hydrastis Canadensis” and “Teucrium Chamaedrys” pp. 826-827, 903, 1177-1179 First Edition Medical Economics Company Montvale, N.J. 1998.*
Johnson “CRC Ethnobotany Desk Reference”Ephedra VulgarisNo. 9747 p. 303 CRC Press 1999.*
Derwent Computer Abstract 2000-326965 Sergeeva O Yu RU2131738 Jun. 20, 1999.*
Derwent Computer Abstract 2000-363087 Sephtein et al RU2133123 Jul. 20, 1999.*
Derwent Computer Abstract 2000-254863 Sergeeva O Yu RU2124898 Jan. 20, 1999.*
Derwent Computer Abstract 1999-079835 Dobrescu RO113805 Nov. 30, 1998.*
Derwent Computer Abstract 1998-284435 Sergee RU2088221 Aug. 27, 1997.*
Castelman “The Healing Herbs” Ephedra pp. 158-160 Rodale Press Emmaus, Pa 1991.
Chernoff Vilhauer McClung & Stenzel LLP
Green Pharmaceuticals, Inc.
Lilling Herbert J.
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