Anti-sense regulation of gene expression in plant cells

Details Anti-sense regulation of gene expression in plant cells Anti-sense regulation of gene expression in plant cells

1988-08-30

1992-04-21

Weimar, Elizabeth C.

Multicellular living organisms and unmodified parts thereof and

Method of introducing a polynucleotide molecule into or...

The polynucleotide alters fat, fatty oil, ester-type wax, or...

4351723, 4352404, 4353201, 536 27, 935 35, 935 36, 935 3, 935 64, 935 67, A01H 104, C12N 1500, C12N 500, C07H 1512

Patent

active

051070650

ABSTRACT:
Regulation of expression of genes encoded for in plant cell genomes is achieved by integration of a gene under the transcriptional control of a promoter which is functional in the host and in which the transcribed strand of DNA is complementary to the strand of DNA that is transcribed from the endogenous gene(s) one wishes to regulate. The integrated gene, referred to as anti-sense, provides an RNA sequence capable of binding to naturally existing RNAs, exemplified by polygalacturonase, and inhibiting their expression, where the anti-sense sequence may bind to the coding, non-coding, or both, portions of the RNA. The antisense construction may be introduced into the plant cells in a variety of ways and be integrated into the plant genome for inducible or constitutive transcription of the anti-sense sequence. A wide variety of plant cell properties may be modifed by employing this technique.
The pCGN978xK12 was deposited at the A.T.C.C. on Mar. 25, 1986, and given Accession No. 67064 and pCGN1401 was deposited on Oct. 7, 1986 at the A.T.C.C. and given Accession No. 67227.

REFERENCES:
patent: 4535060 (1985-08-01), Comai
patent: 4801540 (1989-01-01), Hiatt et al.
Goodman et al., 1987, Science 236:48-54.
Horsch et al., 1984, Science, 223:496-498.
Comai et al., 1985, Nature 317:741-744.
Izant et al., 1984, Cell 36:1007-1015.
Slater et al., 1985, Plant Mol. Biol. 5:137--147.
Grierson et al., 1985, Planta 163:263-271.
Fromm et al., 1985, Proc. Natl. Acad. Sci., U.S. A. 82:5824-5828.
Coleman et al., 1984, Cell 37:429-436.
Chang et al., 1985, Mol. Cell. Biol. 5(9):2341-2348.
Ecker et al., 1986, Proc. Natl. Acad. Sci. 83:5372-5376.
Grierson et al., 1986, Nucleic Acids Research 14(21):8595-8603.
Rosenberg et al., Nature (1985) 313:703-706.
Kim et al., Cell (1985) 42:129-138.
Izant and Weintraub, Science (1985) 229:345-352.
Melton, PNAS U.S.A. (1985) 82:144-148.
Coleman et al., Nature (1985) 315:601-603.
Rubenstein et al., C.R. Acad. Sc. Paris (1984).
Eckert and Davis, Proc. Natl. Acad. Sci. U.S.A. (1986) 83:5372-5376.
DellaPenna et al., Proc. Natl. Acad. Sci. U.S.A. (1986) 83:6420-6424.
Crowley et al., Cell (1985) 43:633-641.
Mansson et al., Chemical Abstracts (1985) 103:211, No. 155198q.
Hobson et al., Chemical Abstracts (1984) 101:416, No. 127096v.
Helmer et al., Biotechnology (Jun. 1984):520-527.
Loesch-Fries et al., Journal of Cellular Biochemistry (1986) vol. 0, No. 10, Part C, p. 41, Abstract No. J108.
Pressey et al., Chemical Abstracts (1982) 97:456, No. 88858x.
Delanuey et al., Proc. Natl. Acad. Sci. U.S.A. (1988) 85:4300-4304.
Sandler et al., Plant Molecular Biology (1988) 11:301-310.
Sheehy et al., Proc. Natl. Acad. Sci. U.S.A. (1988) 85:8805-8809.
Rothstein et al., Proc. Natl. Acad. Sci. U.S.A. (1987) 84:8439-8443.
Smith et al., Nature (1988) 334:724-726.
Preiss et al., Nature (1985) 313:27-32.
Andrew Travers, Nature (1964) 311: 410.
Weintraub et al., TIG (1985) 1:22-25.
McGarry et al., Proc. Natl. Acad. Sci. U.S.A. (1986) 83:399-403.
Pestka et al., Proc. Natl. Acad. Sci. U.S.A. (1984) 82:7525-7528.
Mizuno et al., Proc. Natl. Acad. Sci. U.S.A. (1984) 81:1966-1970.

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