Anti-scarring ribozymes and methods

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C435S006120, C435S091100, C435S091310, C435S320100, C435S455000, C536S023100, C536S024500

Reexamination Certificate

active

07462602

ABSTRACT:
Methods and compositions for treating scarring conditions associated with increased expression of connective tissue growth factor (CTGF). Aspects of the invention include ribozymes that cleave mRNA targets required for CTGF expression, cells containing anti-CTGF ribozymes and vectored anti-CTGF ribozymes suitable for delivery to cellular targets capable of CTGF expression.

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