Anti-retroviral moronic acid derivatives

Details Anti-retroviral moronic acid derivatives Anti-retroviral moronic acid derivatives

2007-10-16

2007-10-16

Zucker, Paul A. (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C560S194000

Reexamination Certificate

active

11134904

ABSTRACT:
The present invention provides moronic acid derivatives of the general formula:which have antiviral activity, along with compositions containing the same and methods of use thereof.

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Kurokawa, M. et al. Anti-Herpes Simplex Virus Activity of Moronic Acid Purified fromRhus javanicaIn Vitro and In Vivo. “The Journal of Pharmacology and Experimental Therapeutics” 289:72-78, 1999.
Ito, J., et al., “Anti-AIDS Agents. 48.1Anti-HIV Activity of Moronic Acid Derivatives and the New Melliferone-Related Triterpenoid Isolated from Brazilian Propolis,”J. Nat. Prod. 64:1278-1281 (2001).

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