Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1977-02-17
1979-08-07
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
546205, 546223, 546224, 546229, 546234, A61K 31445, C07D21158, C07D21126
Patent
active
041637895
ABSTRACT:
This invention relates to piperidine derivatives. More particularly, the invention relates to substituted benzoic acid amides of N-substituted piperidine and to pharmaceutical compositions thereof, which are useful in antagonizing the effects of dopamine or dopaminergic agents of endogenous or exogenous origin and in treating nausea and vomiting resulting from gastrointestinal disorders, congestive heart failure, post operative conditions, etc., other gastrointestinal disorders such as dyspepsia, flatulence, bile regurgitations, hiatus hernia, peptic ulcer, reflux aerophagitis, gastritis, duodenitis, and cholethiasis, and a variety of conditions affecting the central nervous system such as acute and chronic psychoses, maniacal psychosis, schizophrenias, serious disturbances of behavior and non-melancholic depressive state and migraine. The invention also relates to methods of preparing piperidine derivatives.
REFERENCES:
patent: 3342826 (1967-09-01), Miller et al.
patent: 3502652 (1970-03-01), Jucker et al.
patent: 3577440 (1971-05-01), Lunsford et al.
patent: 3963745 (1976-06-01), Cale et al.
patent: 4021567 (1977-05-01), Kaplan et al.
Mauri Jacinto M.
Spickett Robert G. W.
Vega-Noverola Armando
Anphar S.A.
Schwartz Richard A.
Trousof Natalie
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