Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2008-09-09
2008-09-09
Saunders, David A. (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S388250, C530S388260, C530S391300
Reexamination Certificate
active
10981300
ABSTRACT:
The present invention is related to antibodies directed to the antigen properdin and uses of such antibodies. In particular, in accordance with the present invention, there are provided fully human monoclonal antibodies directed to the antigen properdin. Nucleotide sequences encoding, and polypeptides comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
REFERENCES:
patent: 5770429 (1998-06-01), Lonberg
patent: 5861156 (1999-01-01), George et al.
patent: 6075181 (2000-06-01), Kucherlapati
patent: 6114598 (2000-09-01), Kucherlapati
patent: 6150584 (2000-11-01), Kucherlapati
patent: 6162963 (2000-12-01), Kucherlapati
patent: 2002/0015701 (2002-02-01), Gupta-Bansal et al.
Whiteman, Leslie Y. et al., “Association of Activated Properdin With Complexes of Properdin With C3,” The Journal of Immunology, vol. 147, 1344-1351, No. 4, Aug. 15, 1991.
International Search Report for International Application No. PCT/US05/39628 dated Jul. 21, 2006.
Written Opinion of the International Searching Authority for International Application No. PCT/US05/39628 dated Jul. 21, 2006.
Green (1999)J. Immunol. Methods231:11-23.
Wells (2000)Chem Biol7:R185-6.
Davis et al. (1999) Cancer Metastasis Rev 18(4):421-5.
Vuagnat et al. (2000)Mol. Immunol. 37:467-478.
Perdikoulis et al. (2001)Biochim. Biophys. Acta1548:265-277.
Gupta-Bansal et al. (2000)Mol. Immunol. 37:191-201.
Gazit-Bornstein Gadi
Keyt Bruce
Senaldi Giorgio
Yang Xiao-Dong
Zapata Gerardo
Amgen Fremont Inc.
Knobbe Martens Olson & Bear LLP
Saunders David A.
VanderVegt F. Pierre
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