Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2008-01-15
2008-01-15
Chen, Stacy B. (Department: 1648)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C424S141100, C424S133100
Reexamination Certificate
active
07318922
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
Hu et al. Journal of Proteome Research 2003; 2:405-412.
Nagaraja et al. Oncogene, 2006, 25:2328-2338.
Sagynaliev et al. Proteomics, 2005, 5:3066-3078.
Waghray et al. Proteomics, 2001, 1:1327-1338.
Bustin et al. TRENDS in Molec. Med. 2002, 8(6): 269-272.
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTIN 2.2.1 [Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTP 2.2.1 [Jul. 12, 2001], NCBI].
Abe, N., et al., “An Increased High-Mobility Group A2 Expression Level is Associated with malignant Phenotype in Pancreatic Exocrine Tissue,”Br J Cancer—89(11):2104-9 (2003) Abstract.
Ando, M., et al., “Selective Apoptosis of Natural Killer-Cell Tumours by I-Asparaginase,”Br J Haematol.,—130(6):860-8 (2005) Abstract.
Aust, G., et al., “Human Thyroid Carcinoma Cell Lines and Normal Thyrocytes: Expression and Regulation of Matrix Metalloproteinase Inhibitor-1 Messenger-RNA and Protein,”Thyroid—7(5):713-24 (1997) Abstract.
Barnes, V.L., et al., “Expression of Embryonic Fibronectin Isoform EIIIA Parallels Alpha-Smooth Muscle Actin in Maturing and Diseased Kidney,”J Histochem Cytochem.—47(6):787-98 (1999) Abstract.
Bea, S., et al., “BMI-1 Gene Amplification and Overexpression in Hematological Malignancies Occur Mainly in Mantle Cell Lymphonas,”Cancer Res.—61(6):2409-12 (2001) Abstract.
Blaschke, V., et al., “Rapid Quantitation of Proinflammatory and Chemoattractant Cytokine Expression in Small Tissue Samples and Monocyte-Derived Dendritic Cells: Validation of a New Real-Time RT-PCR Technology,”J Immunol Methods.—246(1-2):79-90 (2000) Abstract.
Buckley, A.R., et al., “Butyrate-Induced Reversal of Dexamethasone Resistance in Autonomouse Rat Nb2 Lymphoma Cells,”Apoptosis.—2(6):518-28 (1997) Abstract.
Caberlotto, L. et al.,“Alterations in Neuropeptide Y Levels and Y1 Binding Sites in the Finders Sensitive Line Rats, A Genetic Animal Model of Depression,”Neurosci Lett.—265(3):191-4 (1999) Abstract.
Caberlotto, L., et al., “Neurokinin 1 Receptor and Relative Abundance of the Short and Long Isoforms in the Human Brain,”Eur J Neurosci.—17(9):1736-46 (2003) Abstract.
Chol, D., et al., “Characterization of Cyclin D2 Expression in Human Endometrium,”J Soc Gynecol Investig.—9(1):41-6 (2002) Abstract.
Couvelard, A., et al., “Human Chorionic Gonadotrophin Beta Expression in Malignant Barrett's Oesophagus,”Virchows Arch.—445(3):279-84 (2004) Abstract.
Dagenais, A., et al., “Downregulation of EnaC Activity and Expression by TNF-Alpha in Alveolar Epithelial Cells,”Am J. Physio Lung Cell Mol Physiol.—286(2):L301-11 (2004) Abstract.
De Boer, C.J., et al., “Involement of the CCNDI Gene in Hairy Cell Leukemia,”Ann Oncol.—7(3):251-6 (1996) Abstract.
Dabieve, F., et al., “Inhibin and Activin Production and Subunit Expression in Human Placental Cells Cultured in Vitro,”Mol Hum Reprod.—6(8):743-9 (2000) Abstract.
Dong, Z., et al., “Expression of Membrane-Type Matrix Metalloproteinases 4, 5, and 6 in Mouse Corneas Infected withP. aeruginosa,” Invest Opthalmol Vis Sci—42(13):3223- (2001) Abstract.
Duchrow, M., et al., “Assessment of Proliferative Activity in Colorectal Carcinomas by Quantitative Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR),”Cancer Invest.—19(6):588-96 (2001) Abstract.
Dyer, J., et al., “Molecular Characterisation of Carbohydrate Digestion and Absorption in Equine Small Intestine,”Equine Vet J.—34(4):349-58 (2002) Abstract.
Egwuagu, C.E., et al., “Suppressors of Cytokine Signaling Proteins are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance,”J Immunol.—168(7):3181-7 (2002) Abstract.
El-Ghrably, I.A., et al., “Intravitreal Invading Cells Contribute to Vitreal Cytokine Milieu in Proliferative Vitreoretinopathy,”Br J Opthalmol.—85(4):461-70 (2001) Abstract.
Eleore, L., et al., “Modulation of the Glutamatergic Receptors (AMPA and NMDA) and of Glutamate Vesicular Transporter 2 in the Rat Facial Nucleus after Axotomy,”Neuroscience—136(1):147-60 (2005) Abstract.
Forsberg, H., et al., “Altered Levels of Scavenging Enzymes in Embryos Subjected to a Diabetic Environment,”Free Radic Res.—24(6):451-9 (1996) Abstract.
Freyschuss, B., et al., “Induction of the Estrogen Receptor by Growth Hormone and Glucocorticoid Substitution in Priminary Cultures of Rat Hepatocytes,”Endocrinology—133(4):1548-54 (1993) Abstract.
Fu, K., et al., “Cyclin D1-Negative Mantle Cell Lymphoma: A Clinocopathologic Study Based on Gene Expression Profiling,”Blood—106(13):4315-21 (2005) Abstract.
Fuchs, A.R., et al., “Oxytocin Receptors in Bovine Cervix: Distrubution and Gene Expression During the Estrous Cycle,”Biol Reprod.—54(3):700-8 (1996) Abstract.
Furuta, J., et al., “Silencing of the Thrombomodulin Gene in Human Malignant Melanoma,”Melanoma Res.—15(1):15-20 (2005) Abstract.
Futcher, B., et al., “A Sampling of the Yeast Proteome,”Mol Cell Biol.,—19(11):7357-68 (1999) Abstract.
George, J., et al., “Pre-translational Regulation of Cytochrome P450 Genes is Responsible for Disease-Specific Changes of Individual P450 Enzymes Among Patients with Cirrhosis,”Biochem Pharmacol.—49(7):873-81 (1995) Abstract.
Giroux, M., et al., “Cyclooxygenase-2 Expression in Macrophages: Modulation by Protein Kinase C-alpha,”J immunol.—165(7):3985-91 (2000) Abstract.
Gnatenko, D.V., et al., “Transcript Profiling of Human Platelets Using Microarray and Serial Analysis of Gene Expression,”Blood—101(6):2285-93 (2003) Abstract.
Godbout, R., et al., “Overexpression of DEAD Box Protein (DDX1) in Neuroblastoma and Retinoblastoma Cell Lines,”J Biol Chem,—273(33):21161-8 (1998) Abstract.
Goldenberg, R.C., et al., “Modulation of Gap Junction Mediated Intercellular Communication in TM3 Leydig Cells,”J Endocrinol.—177(2):327-35 (2003) Abstract.
Golebiowski, F., et al., “Expression Level of Ubc9 Protein in Rat Tissues,”Acta Biochim Pol.—50(4):1065-73 (2003) Abstract.
Grem, J.L., et al., “Thymidine Kinase, Thymidylate Synthase, and Dihydropyrimidine Dehydrogenase Profiles of Cell Lines of the National Cancer Institute's Anticancer Drug Screen,”Clin Cancer Res.—7(4):999-1009 (2001) Abstract.
Grenback, E., et al., “Galanin Pituitary Adenomas,”Regul Pept,—117(2):127-39 (2004) Abstract.
Gromova, I., et al., “Protein Abundance and mRNA Levels of the Adipocyte-Type Fatty Acid Binding Protein Correlate in Non-Invasive and Invasive Bladder Transitional Cell Carcinomas,”Int J. Oncol.—13(2):379-83 (1998) Abstract.
Guo, Y., et al., “The Pathogenic Role of Macrophage Migration Inhibitory Factor in Acute Respiratory Distress Syndrome,” Zhinghua Jie He He Hu Xi Za Zhi—25(6):337-40 (2002) Abstract.
Habu, Y., et al., “Restored Expression and Activity of Organic Ion Transporters rOAT1, rOAT3 and rOCT2 after Hyperuricemia in the
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Smith Victoria
Watanabe Colin K.
Barnes Elizabeth M.
Chen Stacy B.
Dreger Ginger R.
Genentech Inc.
Kresnak Mark T.
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