Anti-plaque compositions comprising a combination of morpholinoa

Details Anti-plaque compositions comprising a combination of morpholinoa Anti-plaque compositions comprising a combination of morpholinoa

1990-10-31

1992-01-21

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 49, A61K 716, A61K 722

Patent

active

050826530

ABSTRACT:
Compositions having improved anti-plaque and anti-gingivitis activity comprises a synergistic combination of a) a morpholinoamino alcohol, such as 3-(4-propylheptyl)-4-(2-hydroxyethyl)morpholine and b) and antibiotic, such as the aminoglycosides, amphenicols, ansamycins, carbapenems, cephalosporins, cephamycins, monobactams, oxacephems, penicillins, lincosamides, macrolides, polypeptides and tetracyclines.

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"The Effect of Octapinol on Dento-Gingival Plaque and Development of Gingivitis", Willard et al., J. Periodontal Pres., vol. 18, pp. 429-437.
(1983) "Effect of Some Polyvalent Cations on Plaque Formation in Vivo", Skjorland et al., Scand. J. Dent. Res., vol. 86, pp. 103-107, (1978).

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