Anti-plaque agents

Details Anti-plaque agents Anti-plaque agents

1977-10-03

1978-12-19

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

26050113, 424 7, 424 52, 424 57, A61K 722

Patent

active

041306376

ABSTRACT:
Novel betaine compounds derived from higher alkyl dimethyl carboxylic acid quaternary ammonium compounds; the process of preparing said betaines; and compositions containing an effective antimicrobial amount of said betaines admixed with a pharmaceutical carrier. These compounds are effective in controlling dental plaque without producing an esthetically unacceptable discoloration of tooth surfaces.

REFERENCES:
patent: 3617439 (1971-11-01), Chapman
Swain et al, Journal of Organic Chemistry, 18, 1087-1091 (1953), "Synthesis of N-Alkyldimethyl Derivatives of W-Amino Acids".
Accepted Dental Therapeutics, 35th edition, (1973) RK 701 A3; pp. 60-64, 193-194, 227-236.

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