Anti-peptic ulcer activity of an extract of a flower of...

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a flower or blossom

Reexamination Certificate

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C424S725000, C514S925000, C514S927000

Reexamination Certificate

active

11205146

ABSTRACT:
A pharmaceutical composition comprising an effective amount of an extract or lyophilized extract or at least one bioactive fraction obtained from the plantWoodfordia fruticosaalong with one or more pharmaceutically acceptable additives/carriers for treating ulcer caused by the conditions such as stress induced ulcer, peptic ulcer, cold restraint induced ulcer, drug induced ulcer and acid induced ulcer, also used as specific inhibitor of gastric H+, K+-ATPase and anti-Helicobacter pyloriactivity.

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patent: 6080401 (2000-06-01), Reddy et al.
patent: 6455077 (2002-09-01), Katiyar et al.
patent: 07126144 (1995-05-01), None
Yoshida, Takashi et al., Chemical & Pharmaceutical Bulletin (1991), 39(5), 1157-62. Woodfordin D and oenothein A, trimeric hydrolyzable tannins of macro-ring structure with antitumor activity, Abstract.
Nair, A.G.R. et al., Indian Journal of Pharmacy (1976), 38(4): 110-111. Polyphenols of the flowers ofWoodfordia fruticosa.
Pavia, D.L. et al., Introduction to Organic Laboratory Techniques, Third Edition, 1988. Saunders College Publishing, U.S.A. Chapter Technique 5: Extraction, The Separatory Funnel, Drying Agents, pp. 541-550.
Green, J., The Herbal Medicine-Maker's Handbook: A Home Manual, 2000. The Crossing Press, U.S.A. Chapter 5: The Extraction Process, pp. 74-77; and, Chapter 6: Solvents, pp. 80-98.

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