Anti-pathogenically effective compositions comprising lytic pept

Details Anti-pathogenically effective compositions comprising lytic pept Anti-pathogenically effective compositions comprising lytic pept

1994-06-08

1997-05-20

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

514 2, 514 21, 530324, A61K 3847

Patent

active

056310072

ABSTRACT:
Anti-pathogenically effective compositions are provided containing a combination of hydrolytic enzymes and lytic peptides as the active agent. Methods of controlling the growth of pathogens using the anti-pathogenically effective compositions are provided. Transgenic plants that contain genes that are able to express lytic peptides and hydrolytic enzymes are also provided.

REFERENCES:
patent: 4810777 (1989-03-01), Zasloff
Bohlmann et al., "Leaf-specific Thionins of Barley--a Novel Class of Cell Wall Proteins Toxic to Plant--pathogenic Fungi and Possibly Involved in the Defence Mechanism of Plants", EMBO Journal, 7(6):1559-1565 (1988).
Boller, T. et al., "Chitinase in Bean Leaves: Induction by Ethylene, Purification, Properties, and Possible Function", Planta, 157:22-31 (1983).
Kauffmann, S. et al., "Biological Function of `Pathogenesis-Related` Proteins: Four PR Proteins of Tobacco Have 1,3-.beta.-Glucanase Activity", EMBO Journal, 6(11): 3209-3212 (1987).
Legrand, M. et al., "Biological Function of Pathogenesis-related Proteins: Four Tobacco Pathogenesis-related Proteins are Chitinases", PNAS, 84:6750-6754 (1987).
Lehrer, R.I. et al., "Synergistic Activity of Rabbit Granulocyte Peptides Against Candida albicans", Infection and Immunity, 52(3):902-904 (1986).
Mauch, F. et al., "Antifungal Hydrolases in Pea Tissue", Plant Physiol., 88:936-942 (1988).
Ogasawara, N et al., Abstract Only, "Agricultural Antimicrobial Agents Containing .beta.-1,3-Glucanase and Chitinase", Chemical Abstracts, 79:13362v (1973).
Schlumbaum, A. et al., "Plant Chitinases are Potent Inhibitors of Fungal Growth", Nature, 324:365-367 (1986).
Selsted, M.E. et al., "Purification, Primary Structure, and Antimicrobial Activities of a Guinea Pig Neutrophil Defensin", Infection and Immunity, 55(9):2281-2286 (1987).
Terry, A.S. et al., "The cDNA Sequence Coding for Prepro-PGS (Prepro-magainins) and Aspects of the Processing of This Prepro-polypeptide", J. Biolog. Chem., 263(12):5745-5751 (1988).

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