Anti-parasitic activity

Details Anti-parasitic activity Anti-parasitic activity

1996-01-25

1998-06-09

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

A61K 31495, A61K 3150

Patent

active

057634424

ABSTRACT:
The invention provides the use of a riminophenazine in the manufacture of a medicament to treat parasitic infections. The riminophenazine may be used for the prophylactic treatments of maleria or for the therapeutic treatment of maleria. A known anti-maleria drug, e.g. chloroquine or mefloquine may be administered as well. The riminophenazine may be a compound of the general formula: ##STR1## wherein: R.sup.1 is selected from hydrogen atoms, halogen atoms, alkyl, alkoxy and trifluoromethyl radicals,

REFERENCES:
patent: 2875204 (1959-02-01), Barry et al.
patent: 2943089 (1960-06-01), Barry et al.
patent: 2946792 (1960-07-01), Barry et al.
patent: 2948726 (1960-08-01), Barry et al.
patent: 3499899 (1970-03-01), Girard et al.
patent: 3592814 (1971-07-01), Barry et al.
patent: 3859667 (1975-01-01), Lau et al.
Van Rensburg. et al., Cancer Lett. (Shannon, Ireland), 1994, vol. 85, No. 1, pp. 59-63 Abstract Only.
Van Rensburg, et al., Int. J. Oncol., 1994, vol. 4, No. 5, pp. 1115-1119 Abstract Only.
Van Rensburg, et al., Int. J. Oncol., 1993, vol. 3, No. 5, pp. 1011-1013.
Anderson, et al., Biochem. Pharmacol., 1993, vol. 46, No. 11, pp. 2029-2038.
Krajewska, et al., Journ. Infect. Dis., 1993, vol. 167, No. 4, pp. 899-904.
Van Rensburg, et al., Cancer Res., 1993, vol. 53, No. 2, pp. 318-323.
Banerjee, et al. Chemotherapy, 1976, vol. 22, No. 3, pp. 242-252.
Il'yushonok et al., Teor. Eksp. Khim., 1977, vol. 13, No. 6, pp. 763-768 Abstract Only.
Ludwig, et al., Chem. Ber., 1982, vol. 115, No. 6, pp. 2380-2383 Abstract Only.
Kondratenko, et al., Teor. Eksp. Khim., 1977, vol. 13, No. 2, pp. 262-266 Abstract Only.
Ott et al., Monatsh. Chem., 1976, vol. 107, No. 4, pp. 879-888 Abstract Only.
Yoshida, et al., Waseda Daigaka Rikogaku Kenkyusho Hokoku, 1973, vol. 61, pp. 34-39.
Anderson, et al., Toxicol. Appl. Pharmacol., 1994, vol. 125, pp. 176-183.
Anderson, et al., Biochem. Pharmacol., 1988, vol. 37, No. 24, pp. 4635-4641.
Barry, et al., Leprosy Review, 1965, vol. 36, pp. 3-7.
Hagan, et al., Leprosy Review, 1979, vol. 50, pp. 129-134.
Franzblau et al., Antimicrobial Agents and Chemotherapy, 1989, vol. 33, No. 11, pp. 2004-2005.
Barry et al., 10G-Heterocyclic Compounds, 1958, vol. 53, p. 1959.
Sheagren, Journal of Parasitology, 1968, vol. 54, No. 6, pp. 1250-1251.
Mackey et al., British Journal of Dermatology, 1974, vol. 91, No. 1, pp. 93-96.
Vischer, Arzneimittel-Forschung (Drug Research), 1970, vol. 20, No. 5, pp. 714-723.
Evans et al., Annals of Tropical Medicine and Parasitology, 1989, vol. 83, No. 5, pp. 447-454.
Singh et al., Indian Journal of Experimental Biology, 1988, vol. 26, No. 1, pp. 48-52.
Mainguet et al., Acta Endoscopica, 1980, vol. 10, No. 4, pp. 307-313.
Arbiser et al., Journal of the American Academy of Dermatology, 1995, vol. 32, No. 21, pp. 241-247.
O'Connor et al., Biochemical Society Transactions, 1995, vol. 23, p. 357S.
O'Sullivan et al., J. Med. Chem., 1988, vol. 31, pp. 567-572.

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