Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1995-01-31
1996-09-03
Weimar, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
A61K 3800, C07K 710, C07K 700
Patent
active
055525229
ABSTRACT:
The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
REFERENCES:
patent: 4626549 (1986-12-01), Molloy et al.
Chem. Abstract 94-304407/38, Nagata Sangyo Co. Ltd. (Mar. 29, 1993).
Zhang, et al., "Positional cloning of the mouse obese gene and its human homologue", Nature, 372:1, 425-432 (Dec. 1, 1994).
Rink, "In search of a satiety factor", Nature, 372:1, 406-407 (Dec. 1, 1994).
Marx, "Obesity Gene Discovery May Help Solve Weighty Problem", Science, 266, 1477-1478 (Dec. 2, 1994).
DiMarchi Richard D.
Flora David B.
Heath, Jr. William F.
Hoffmann James A.
Shields James E.
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Marshall S. G.
Weimar Elizabeth C.
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