Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1995-03-17
1998-02-17
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530324, 514 12, A61K 3800, C07K 1400
Patent
active
057192669
ABSTRACT:
The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
REFERENCES:
patent: 4626549 (1986-12-01), Molloy et al.
Chem. Abstract 94-304407/38, Nagata Sangyo Co. Ltd. Mar. 29, 1993.
Zhang, et al., "Positional cloning of the mouse obese gene and its human homologue", Nature, 372:1, 425-432 Dec. 1, 1994.
Rink, "In search of a satiety factor", Nature, 372:1, 406-407 Dec. 1, 1994.
Flam, "Obesity Gene discovery May Help Solve Weighty Problem", Science, 266, 1477-1478 Dec. 2, 1994.
DiMarchi Richard D.
Hermeling Ronald N.
Hoffmann James A.
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Marshall S. G.
Tsang Cecilia J.
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