Anti-obesity agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514178, 550542, 550543, 550544, A61K 31575, C07J 900

Patent

active

058469621

ABSTRACT:
Anti-obesity agents which comprise 3-ketosteroid compounds as an active ingredient are provided. The anti-obesity agents of the present invention have a high anti-obesity effect with little or no side effects and toxicity. Food products which contain anti-obesity agents comprising 3-ketosteroid compounds as an active ingredient, pharmaceutical compositions which comprise 3-ketosteroid compounds as an active ingredient and pharmaceutically acceptable carriers, and methods for preventing and treating obesity which comprise administering an effective amount of a 3-ketosteroid compound to a human are also provided.

REFERENCES:
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patent: 4477445 (1984-10-01), Philibert et al.
patent: 4897390 (1990-01-01), Ruhe
patent: 5420121 (1995-05-01), Suzuki
G.B. Forbes et al., Hormonal Response to Overfeeding, Am. J. Clin. Nutr.; 49:608-11 (1989).
L. Abrahamsson & H. Hackl, Catabolic Effects and the Influence on Hormonal Variables Under Treatment with Gynodian-Depot.RTM. or Dehydroepiandrosterone (DHEA) Oenanthate, Maturitas, 3:225-234, (1981).
K. Kusuhara et al., The Pathogenesis of Amenorrhea Related with Simple Weight Loss, Jpn. J. Fertil. Steril., 26:7-15 (1981). (Japanese with English language summary).

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