Anti-myosin mouse monoclonal antibody and method of use for diag

Details Anti-myosin mouse monoclonal antibody and method of use for diag Anti-myosin mouse monoclonal antibody and method of use for diag

1994-05-31

1997-05-06

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

5303882, 53038825, 5303913, A61K 5110, C12N 1520, A07K 1618

Patent

active

056268300

ABSTRACT:
A monoclonal antibody or antigen binding fragment thereof which recognizes light meromyosin fragments of .alpha.- and .beta.-type human cardiac myosin heavy chains that remain in situ after myocardial cell death is described. The antibody is produced by the hybridoma having the accession number ATCC HB9916. The antibody or antigen binding fragment thereof does not cross-react with human myosin light chains. The monoclonal antibody or antigen binding fragment thereof, in a labeled form is capable of producing an image of both ventricular and atrial damage resulting from myocardial cell necrosis and is capable of producing an image of a cell or tissue expressing myosin.

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