Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1987-08-18
1990-08-21
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514529, A61K 3122, A61K 31215
Patent
active
049506862
ABSTRACT:
An anti-mycoplasma agent comprising tropolone, its derivatives, represented by the formula: ##STR1## (wherein R.sub.1 is hydroxy, aliphatic acyloxy, arylacyloxy, arysulfonyloxy, carboxyalkyloxy or its ester, benzoylalkyloxy, alkenyloxy, 1,3-dihydro-3-oxo-1-isobenzofuranyloxy, (2-oxo-5-methyl-1,3-dioxol-4-yl)methyloxy or thiocyanato and R.sub.2 is hydrogen, halogen, hydroxy, alkyl or alkoxy) and their salts as an active ingredient, which has potent activity especially against tylosin-resistant mycoplasma both in vitro and in vivo and is effectively used in treating the diseases caused thereby.
REFERENCES:
Chemical Abstracts 75:61884m (1971).
Chemical Abstracts, Formula Index, Jul. & Dec. 1971, p. 345F.
Hattori Teruo
Hayashi Yoshiyuki
Kondo Eiji
Konishi Takao
Shoji Jun'ichi
Goldberg Jerome D.
Shionogi & Co. Ltd.
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