Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-10-13
1997-03-04
Fox, David T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530370, C07K 1400
Patent
active
056079192
ABSTRACT:
Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.
Bojsen Kirsten
Kragh Karsten M.
Mikkelsen J.o slashed.rn D.
Nielsen John E.
Nielsen Klaus K.
Fox David T.
Marcus-Wyner Lynn
McElwain Elizabeth F.
Sandoz Ltd.
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