Anti microbial mafenide-phosphanilate compound, pharmaceutical c

Details Anti microbial mafenide-phosphanilate compound, pharmaceutical c Anti microbial mafenide-phosphanilate compound, pharmaceutical c

1991-10-24

1993-04-06

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

562 11, A61K 31685, C07F 938

Patent

active

052004023

ABSTRACT:
The present invention relates to a synergistic antimicrobial compound (mafenide-phosphanilate) having especially high activity for topical prophylaxis and therapy of burn wound infections. The invention further relates to anti-microbial pharmaceutical compositions and a method for treating microbial infection. More particularly, the invention relates to the effective unexpectedly improved treatment of burn wounds involving Pseudomonas and Proteus bacteria.

REFERENCES:
patent: 2288531 (1942-06-01), Klarer
patent: 3497599 (1970-02-01), Nachod
patent: 3694447 (1972-09-01), Pagano
patent: 3794723 (1974-02-01), Pagano
patent: 4125610 (1978-11-01), Redl
patent: 4666896 (1987-05-01), Warner et al.

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