Anti-metastatic factor

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Derived from musculoskeletal system – other than cardiac muscle

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Details

530350, 530841, 514356, C01C 1244, A61K 3144, A61K 300

Patent

active

052426920

ABSTRACT:
A factor isolable from muscle tissue or muscle cell culture inhibits proliferation of tumor cells, such as ESB, HT-29 and B-16 F1 cell lines, as well as the peripheral white blood cells of a patient with chronic myeloid leukemia. The active fraction has a molecular weight in the range of 25-30,000 daltons.

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patent: 4356261 (1982-10-01), Kuettner
patent: 4690935 (1987-09-01), Taylor et al.
patent: 4822607 (1989-04-01), Balassa et al.
patent: 4950680 (1990-08-01), Taylor et al.
Schirmacher V., Tumor Metastases and Cell-Mediated Immunity in a Model System in DBA/2 Mice. V. Transfer of Protective Immunity with H-2 Identical Immune T cells from B10.D2 Mice, Int. J. Cancer, 1979, 233-234.
Nichols, W. W. et al., Characterization of a new Human Diploid Cell Strain, IMR-90., Science, 1977, 196, 60-63.

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