Anti-melanoma antibody MG-21 for diagnosis and therapy of human

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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43524027, 435188, 530389, 530390, 530391, 424 8591, 424 858, 424 11, 436548, A61K 3516, C12N 1506

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050555596

ABSTRACT:
An antibody MG-21 which is directed against a tumor-associated glycolipid antigen and which is capable of activating serum complement or antibody dependent cellular cytoxicity is described. This antibody finds use in the therapy of cancers particularly melanoma and glioma. Proper administration of the antibody results in lysis of the tumor cells in vivo.

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