Anti-leukemic oxygenated benzo[c]phenanthridine compounds

Details Anti-leukemic oxygenated benzo[c]phenanthridine compounds Anti-leukemic oxygenated benzo[c]phenanthridine compounds

1975-03-10

1977-03-29

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260289C, 260289AZ, C07D21716

Patent

active

040148858

ABSTRACT:
5,6-Dihydro-6-alkoxynitidine compounds of the formula ##STR1## wherein R.sub.1 and R.sub. 2 are selected independently from the group consisting of C.sub.1 -C.sub.6 alkyl groups, H and benzyl or R.sub.1 and R.sub.2 taken together are methylene and R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are selected independently from the group consisting of C.sub.1 -C.sub.6 alkyl groups, H and benzyl are anti-leukemic agents.

REFERENCES:
bailey et al., J. Chem. Soc., (1950) p. 2277.
Zee-Cheng et al., J. Pharm. Sci., vol. 59, (1970) pp. 1630-1632.
Wall et al., 162nd ACS Meeting, (1971) MEDI-34.

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