Anti-LAM 1-3 antibody and hybridoma

Details Anti-LAM 1-3 antibody and hybridoma Anti-LAM 1-3 antibody and hybridoma

1994-03-21

1998-07-07

Feisee, Lila

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Animal cell, per se, expressing immunoglobulin, antibody, or...

435326, 435332, 435334, 435343, 5303871, 5303873, 5303881, 53038822, 5303887, 53038873, 53038875, 5303913, C07K 1618, C07K 1628, C12N 512

Patent

active

057767750

ABSTRACT:
A hybridoma cell line produced by the fusion of NS-1 myeloma cells with spleen cells obtained from mice immunized with Leukocyte Adhesion Molecule-1 (LAM-1) cDNA transfected cells. The cell line produces a monoclonal antibody reactive with human, monkey, cow, rabbit, sheep, dog, cat, pig and goat LAM-1. The monoclonal antibody produced by the cell line, anti-LAMl-3, may be clinically useful in blocking leukocyte entry into sites of inflammation or tissue injury.

REFERENCES:
patent: 5098833 (1992-03-01), Lasky
L. Flaherty et al., "A monoclonal antibody (MAb) to L-selectin does not prevent neutrophil (PMN) emigration into an inflamed peritoneal cavity," The Faseb Journal USA 6: p. A1889.
Harris et al. Tibtech 11:42-45 (1993).
Ward Therapeutic Immunol. 1:165-171 (1994).
Reinhen F et al J. Immunol. 128:463-468 1982.
Tedder et al. J Immunol. 144:532-540 (1990).
Gatenby et al. J. Immunol 129:1997-2000 (1982).
Kishimoto et al. PNAS 87:2244-2248 (1990).
Spertini et al. J Immunol. 147:942-949 (1991).
Bowen et al. J. Cell Biol. 109:421-427 (1989).
Tedder et al. J. Exp Med 170:123-133 (1989).
Wu et al. J Cell Biol 107:1845-1851 (1988).
Morrison Science 229:1202-1207 (1985).

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