Anti-lafora body monoclonal antibody

Details Anti-lafora body monoclonal antibody Anti-lafora body monoclonal antibody

1987-07-13

1990-10-09

Moskowitz, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

530387, 435 7, 435 7021, 436548, 935104, 935108, 935110, C07K 1528, C12N 520, G01N 33535, G01N 3353

Patent

active

049620320

ABSTRACT:
A monoclonal antibody is disclosed capable of reacting with abnormal glycogen from patients with Lafora disease (Lafora bodies) and with abnormal glycogen from patients with type IV glycogenosis but not with normal glycogen, and therefore useful in the diagnosis of Lafora disease and type IV glycogenosis (Andersen's disease).

REFERENCES:
Yokota, T. et al., "Immunological Homogeneity of Lafora Body, Corpora Amylacea, Basophilic Degeneration in Heart, and Intracytoplasmic Inclusions of Liver and Heart in Type IV Glycogenosis", Acta Pathol. Jpn., 37(6): 941-946, 1987.
Goding, J. W., Monoclonal Antibodies: Principles and Practice, Academic Press, Inc., Orlando, 1984, pp. 56-97, 1984.
Sakai, M. et al., "Studies in Myoclonus Epilepsy (Lafora Body Form) II., Polyglucosans in the Systemic Deposits of Myoclonus Epilepsy and Corpora Amylacea", Neurology, 20: 160-176, Feb. 1970.
Kamei, J. Clin. Elec. Mic., vol. 17 (1984) 909:10
Robitaille, Brain, vol. 103 (1980) 315:36.
Chemical Abstracts, vol. 84, No. 13, (1976), p. 343, 87689n.

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