Anti-influenza M2e antibody

Details Anti-influenza M2e antibody Anti-influenza M2e antibody

2009-11-20

2011-12-20

Boesen, Agnieszka (Department: 1648)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S135100, C424S141100, C424S139100, C424S142100, C424S209100

Reexamination Certificate

active

08080244

ABSTRACT:
Humanized recombinant and monoclonal antibodies specific for the ectodomain of the influenza virus M2 ion channel protein are disclosed. The antibodies of the invention have anti-viral activity and may be useful as anti-viral therapeutics and/or prophylactic/vaccine agents for inhibiting influenza virus replication and for treating individuals infected with influenza.

REFERENCES:
patent: 2005/0170334 (2005-08-01), Mikayama et al.
patent: 2009/0162366 (2009-06-01), Mikayama et al.
Zhan et al. (Molecular Immunology, 2006, vol. 43, p. 2195-2206).
Delagrave et al. (Protein Engineering 1999, vol. 12, p. 357-362).
Di Niro et al. (BMC Biotechnology, 2007, vol. 7, p. 1-10).

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