Anti-inflammatory products derived from methylene-diphosphonic a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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558155, 562 13, 562 21, A61K 3166, C07F 938

Patent

active

048762482

ABSTRACT:
The present invention relates to products of the formula ##STR1## where R.sub.1 is H or alkyl, n is an integer from 0 to 10, and R.sub.2 is chosen from amongst H, unsubstituted or substituted alkyl radicals, a ##STR2## group, a substituted or unsubstituted phenyl radical, a ##STR3## group, where X is oxygen or sulfur, or a heterocyclic radical with 5 or 6 members, which may or may not be fused to a benzene ring and R.sub.3 is H or OH.
The present invention also relates to a process for the preparation of the products of the formula (I), and to the drugs, having in particular an anti-inflammatory effect, containing a product of formula (I).

REFERENCES:
patent: 3299123 (1967-01-01), Fitch et al.
patent: 3654151 (1972-04-01), King et al.
patent: 3683080 (1972-08-01), Francis
patent: 3705191 (1972-12-01), Kerst
patent: 3957858 (1976-05-01), Kent
patent: 4071584 (1978-01-01), Berien
patent: 4171373 (1979-10-01), Diamond
patent: 4264582 (1981-04-01), Flora et al.

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