Anti-inflammatory lipoxin B analogs

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

560103, 556482, 260413, C09F 500

Patent

active

045767580

ABSTRACT:
The present invention relates to analogs of lipoxin B (LX-B) and discloses the anti-inflammatory uses for these analogs. Particularly, the present invention relates to analogs of 5D,14,15-trihydroxy-6,8,10,12-eicosatetraenoic acid, including certain 5-epi-, 8,9-didehydro-, 6-iso, 6,7-dihydro-7.alpha.-hydroxy, and 6,7-dihydro-7.beta.-hydroxy derivatives.

REFERENCES:
patent: 2934570 (1960-04-01), Goldberg et al.
patent: 3972907 (1976-08-01), Baran et al.
patent: 4112224 (1978-09-01), Bundy
patent: 4264517 (1981-04-01), Liang
Jubiz, W., et al., Biochem. Biophys. Res. Commun. 99:976-986 (1981).
Radmark, O., et al., In: Advances in Prostaglandin, Thromboxane & Leukotriene Research, vol. 11, pp. 61-70, Raven Press, NY (1982).
Maas, R. L., et al., Proc. Natl. Acad. Sci. 78:5523-5527 (1981).
Lagarde, M., et al., Biochem. Biophys. Res. Commun. 99:1398-1402 (1981).
Vanderhoek, J. Y., et al., J. Biol. Chem. 255:5996-5998 and 255:10064-10066 (1980).
Samuelsson, B., Science 220:568-565 (1983).
Weissman, G., et al., N. Engl. J. Med. 303:27-34 (1980).
Serhan, C. N., J. Immunol. 125:2020-2024 (1980).
Lewis, R. A., et al., J. Exp. Med. 154:1243-1248 (1981).
Serhan, C. N., et al., Biochem. Biophys. Res. Commun. 107:1006-1012 (1982).
Lundgerg, U., et al., FEBS Lett. 126:127-132 (1981).
Maas, R. L. et al., Proc. Natl. Acad. Sci. 80:2884-2888 (1983).
Sok, D-E, et al., Biochem. Biophys. Res. Commun. 104:1363-1370 (1981).
Sok, D-E, et al., Biochem. Biophys. Res. Commun. 110:273-279 (1983).
Turk, J., et al., J. Biol. Chem. 257:7068-7076 (1982).
Turk, J. et al., Biochim. Biophys. Acta 750:78-90 (1983).
Turk, J. et al., Advances in Prostaglandin, Thromboxane & Leukotriene Research, vol. 11, pp. 123-132, Raven Press, N.Y. (1983).
Maas, R. L., et al., J. Biol. Chem. 257:7056-7067 (1982).
Maas, R. L., et al., Leukotrienes and Other Lypoxygenase Products, Raven Press, N.Y. (1982), pp. 29-44.
Serhan, C. N., Biochem. Biophys. Res. Commun. 118:943-949 (1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Anti-inflammatory lipoxin B analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-inflammatory lipoxin B analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-inflammatory lipoxin B analogs will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2304872

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.