Anti-inflammatory factor, method of isolation, and use

Details Anti-inflammatory factor, method of isolation, and use Anti-inflammatory factor, method of isolation, and use

1994-10-03

1997-07-22

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Milk or colostrum

4242781, 514 54, 536 221, A61K 3520

Patent

active

056501757

ABSTRACT:
The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor resulting in substantially or highly purified preparations and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.

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patent: 4284623 (1981-08-01), Beck
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patent: 4636384 (1987-01-01), Stolle et al.
patent: 4732757 (1988-03-01), Stolle et al.
patent: 4897265 (1990-01-01), Stolle et al.
patent: 4956349 (1990-09-01), Beck
patent: 5352462 (1994-10-01), Beck
Goldman, A. S. et al., "Antiflammatory Properties of Human Milk," Acta Paediatr. Scand. 75:689-695 (1986).
English translation of Japanese Unexamined Patent Publication No. 26312/1978; Application No. 99385/1976, published Mar. 11, 1978.
Owens, W.E. et al., Evaluation of an Anti-Inflammatory Factor Derived from Hyperimmunized Cows, Proc. Soc. Exp. Biol. Med. 190(1): 79-86 (1989).

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