Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-12-23
1985-05-28
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546316, 546323, 546337, 546335, 549 64, 549450, 514355, 514443, 514469, C07D21356, A61K 3142
Patent
active
045200270
ABSTRACT:
The invention concerns novel esters of 4-(1-hydroxy-2-[(acylamino)alkylamino]ethyl)phenols of the formula: ##STR1## and salts thereof, wherein R.sup.1 and R.sup.2 are (3-5C)alkyl, R.sup.3 and R.sup.4 are hydrogen or methyl, A is a direct bond or methylene, and Q is various heteroaromatic containing groups. The esters possess topical anti-inflammatory properties and the invention provides pharmaceutical compositions containing the esters and processes for their chemical manufacture.
REFERENCES:
patent: 4303649 (1981-12-01), Jones
patent: 4323575 (1982-04-01), Jones
patent: 4355045 (1982-10-01), Preston
Marsham Peter R.
Thomson David S.
Imperial Chemical Industries plc
Rotman Alan L.
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