Anti-inflammatory androstane derivative

Details Anti-inflammatory androstane derivative Anti-inflammatory androstane derivative

2006-09-05

2006-09-05

Badio, Barbara P. (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C540S114000

Reexamination Certificate

active

07101866

ABSTRACT:
According to one aspect of the invention, there is provided a compound of formula (I)and solvates thereof. There are also provided compositions containing the compound, processes for preparing it, and its use in therapy.

REFERENCES:
patent: 3755302 (1973-08-01), Ercoli et al.
patent: 4221787 (1980-09-01), Bodor et al.
patent: 4335121 (1982-06-01), Phillipps et al.
patent: 4472393 (1984-09-01), Shapiro
patent: 5081113 (1992-01-01), Claussner et al.
patent: 5658549 (1997-08-01), Akehurst et al.
patent: 5837699 (1998-11-01), Sequeira et al.
patent: 5889015 (1999-03-01), Sequeira et al.
patent: 6057307 (2000-05-01), Sequeira et al.
patent: 6127353 (2000-10-01), Yuen et al.
patent: 6136294 (2000-10-01), Adjei et al.
patent: 6197761 (2001-03-01), Biggadike et al.
patent: 6261539 (2001-07-01), Adjei et al.
patent: 6537983 (2003-03-01), Biggadike et al.
patent: 889563 (1981-11-01), None
patent: 1059906 (1959-06-01), None
patent: 2031205 (1971-02-01), None
patent: 0389368 (1990-09-01), None
patent: 0389369 (1990-09-01), None
patent: 0470617 (1992-02-01), None
patent: 1296458 (1972-11-01), None
patent: 8291072 (1996-11-01), None
patent: 8291073 (1996-11-01), None
patent: WO 89/03390 (1989-04-01), None
patent: WO 97/21721 (1997-06-01), None
patent: WO 97/21724 (1997-06-01), None
patent: WO 97/40836 (1997-11-01), None
patent: 98/17676 (1998-04-01), None
patent: 00/16814 (2000-03-01), None
patent: 00/33892 (2000-06-01), None
patent: WO 00/49993 (2000-08-01), None
patent: WO 00/66522 (2000-11-01), None
patent: 01/54664 (2001-08-01), None
patent: WO 03/066656 (2003-08-01), None
Knobil, K., et al., “Adding Salmeterol is More Effective than Increasing the Dose of Fluticasone for Patients with Asthma who are Symptomatic on Low Dose Fluticasone,” European Respiratory Review, Copenhagen, DK, vol 12, No. SUPPL 29, Dec. 1998, pp. 19S-20S, XP000992769.
Shapiro, E.L., et al., “17 Heteroaroyl Esters of Corticosteroids 2. 11-Beta Hydroxy Series,” Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 30, No. 9, 1987, pp. 1581-1588, XP002153839.
Phillipps, G.H., et. al., “Synthesis and Structure-Activity Relationships in a Series of Antiinflammatory Corticosteroid Analogues, Halomethyl Androstane-17β-carbothioates and -17β-carboselenoates,” Journal of Medicinal Chemistry 1994, 37, 3717-3729.
U.S. application Ser. No.: 10/066,964 filed Feb. 4, 2002.
U.S. application Ser. No.: 10/066,836 filed Feb. 4, 2002.
U.S. application Ser. No.: 10/066,951 filed Feb. 4, 2002.
U.S. application Ser. No.: 10/067,010 filed Feb. 4, 2002.
U.S. application Ser. No.: 10/067,020 filed Feb. 4, 2002.
U.S. application Ser. No.: 10/200,364 filed Jul. 22, 2002.
U.S. application Ser. No.: 10/241,658 filed Sep. 11, 2002.
U.S. application Ser. No.: 10/281,735 filed Oct. 28, 2002.
Sakagami et al., “Mucoadhexive BDP microspheres for powder inhalation-their unique pharmacokinetic-pharmacodynamic profiles,”Repiratory Drug Delivery VI,pp. 193-199 (1998).
PCT/GB01/03495 Written Opinion, date of mailing Apr. 4, 2002.
PCT/GB01/03495 International Preliminary Examination Report, date of Mailing Aug. 30, 2002.
Pharmacokinetics of GW685698X and CC118781 (Fluticasone Propionate) when Co-Administered by the Intratracheal or Intravenous Route to the Anaethetised White Pig (Study No. 03DMW062) 2004.
The Pharmacokentics of GW685698X and CC118781 Following Intracheal Co-Administration to the Anaesthetised White Pig (Study No. B30947) 2003.

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