Anti-inflammatory and anti-pyretic method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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514549, 514675, 514562, A61K 31225

Patent

active

059944021

ABSTRACT:
A method of reducing or inhibiting inflammation and inducing or promoting anti-pyresis comprises administering to a mammal in need of such treatment, an amount of a glutathione depleting agent effective to reduce or inhibit neutrophil sequestration at the inflammation site. The agent may be administered as a pharmaceutical composition including a carrier. Examples of the agent itself are diethylmaleate (DEM), phorone, buthionine-sulfoximine (BSO), glutathione depleting diethylmaleate (DEM) mimetics, glutathione depleting phorone mimetics and glutathione depleting buthionine sulfoximine (BSO) mimetics.

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