Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1997-02-07
1999-11-30
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514549, 514675, 514562, A61K 31225
Patent
active
059944021
ABSTRACT:
A method of reducing or inhibiting inflammation and inducing or promoting anti-pyresis comprises administering to a mammal in need of such treatment, an amount of a glutathione depleting agent effective to reduce or inhibit neutrophil sequestration at the inflammation site. The agent may be administered as a pharmaceutical composition including a carrier. Examples of the agent itself are diethylmaleate (DEM), phorone, buthionine-sulfoximine (BSO), glutathione depleting diethylmaleate (DEM) mimetics, glutathione depleting phorone mimetics and glutathione depleting buthionine sulfoximine (BSO) mimetics.
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Nathens Avery B.
Rotstein Ori D.
Amzel Viviana
MacMillan Keith D.
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