Anti-inflammatory and analgesic compounds, related compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514673, 424663, 424664, 424665, 424583, A61K 31195

Patent

active

051807432

ABSTRACT:
This application relates to an anti-inflammatory, immunosuppressive and analgesic composition, a method for its preparation, a pharmaceutical composition including it and a method of treating auto-immune diseases. The anti-inflammatory, immunosuppressive and analgesic compound is derived from ant venom extract which has been purified of contamination by a variety of non-active components present in crude ant venom extracts. A synthetic venom has also been prepared from various components. The related pharmaceutical composition has been shown to be effective in treating and alleviating the symptoms of auto-immune diseases, particularly rheumatoid arthritis.

REFERENCES:
patent: 4247540 (1981-01-01), Holtzmann
Hink et al. Inflammation 13(2): 175-184 (1989).
Skoog et al. Fundamentals of Analytical Chemistry, 1963 Holt, Rhinehart & Winston, New York pp. 668-669.
Byrnes et al. Clin Res 33(2): Abstr. 590A (1985).

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