Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Cancer cell or component thereof
Patent
1982-04-12
1984-03-06
Raymond, Richard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Cancer cell or component thereof
549 38, A61K 31385, C07C33906
Patent
active
044354207
ABSTRACT:
N-(1,3-dithiolan-2-ylidene)-4-alkylanilines are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.
REFERENCES:
patent: 3442907 (1969-05-01), Donche et al.
patent: 3489771 (1970-01-01), Donche et al.
patent: 4060628 (1977-11-01), Enders et al.
patent: 4131683 (1978-12-01), Harrison et al.
patent: 4172941 (1979-10-01), Harrison et al.
Nakai et al., Tetrahedron Letters, 39 (1967) pp. 3835-3838.
Doherty Niall S.
Harrison Boyd L.
Kolano John J.
McDonald Raymond A.
Merrell Dow Pharmaceuticals
Raymond Richard
Street Gary D.
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