Anti-inflammatory agents and antiasthmatic agents

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Cancer cell or component thereof

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549 38, A61K 31385, C07C33906

Patent

active

044354207

ABSTRACT:
N-(1,3-dithiolan-2-ylidene)-4-alkylanilines are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.

REFERENCES:
patent: 3442907 (1969-05-01), Donche et al.
patent: 3489771 (1970-01-01), Donche et al.
patent: 4060628 (1977-11-01), Enders et al.
patent: 4131683 (1978-12-01), Harrison et al.
patent: 4172941 (1979-10-01), Harrison et al.
Nakai et al., Tetrahedron Letters, 39 (1967) pp. 3835-3838.

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