Anti-inflammatory 4,5-diaryl-.alpha.-(polyfluoroalkyl)-1H-pyrrol

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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548561, 424263, 546256, 546281, 564251, 564185, 564383, 568425, 568812, 570128, A61K 3140, A61K 3144, C07D207335, C07D40104

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active

043351360

ABSTRACT:
4,5-Diaryl-.alpha.-(polyfluoroalkyl)-1H-pyrrole-2-methanamines such as 4,5-bis(4-fluorophenyl)-.alpha..alpha.-bis-(trifluoromethyl)-1H-pyrrole-2- methanamine, useful in treatment of inflammation.

REFERENCES:
patent: 3564016 (1971-02-01), Schoen et al.
patent: 3709906 (1973-01-01), Yoshida et al.
Szmuszkovicz et al., J. Med. Chem., vol. 9, p. 527 (1966).
Chemical Abstracts, vol. 84, Abstract No. 180032c (1976).

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