Anti-inflammatory 3-benzofuranyl imidazothiazole

Details Anti-inflammatory 3-benzofuranyl imidazothiazole Anti-inflammatory 3-benzofuranyl imidazothiazole

1978-03-02

1979-07-10

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424270, C07D27708

Patent

active

041607686

ABSTRACT:
Certain imidazothiazoles and thiazolopyrimidines have been found to prevent and inhibit the formation of granuloma tissue in animals. This result is accomplished by administering to the animal subject a therapeutically effective amount of a compound having the formula: ##STR1## WHEREIN R is hydrogen or methyl, R' is hydrogen, lower alkyl or thioalkyl, carboxy methyl, or phenyl; R" is lower alkyl, 2-benzofuranyl, naphthyl, phenyl, or mono- or disubstituted phenyl. The hydrated precursors of certain of these compounds as well as the acid addition and quaternary salts of both the compounds and their hydrated precursors may be employed.

REFERENCES:
patent: 3853872 (1974-12-01), Wei et al.
patent: 3890341 (1975-06-01), Gordon et al.

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