Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

Details Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles

1991-06-28

1992-05-26

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 548181, 548465, 548468, C07D40704, C07D40904, C07D41704, A61K 3140

Patent

active

051168545

ABSTRACT:
Certain 1-heteroaryl-3-acyl-2-oxindoles wherein the acyl-substituent is thenoyl, furoyl, benzoyl or substituted benzoyl, are inhibitors of cycloxygenase and lipoxygenase enzymes and are useful as anti-inflammatory agents in mammals.

REFERENCES:
patent: 4053613 (1977-10-01), Rovnyak
patent: 4752609 (1988-06-01), Kadin

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