Anti-infective methods and compositions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514263, A61K 31135, A61K 3152

Patent

active

048732656

ABSTRACT:
Methods of providing local anti-infective treatment to a human or animal tissue area requiring such treatment comprise the application to the affected tissue area of an effetive amount of a composition containing from 0.5 to 5% by weight of selected antihistaminic agents in pharmaceutically acceptable topical vehicles including liquids, lotions, aerosols, creams, gels and ointments.

REFERENCES:
Martindale Pharmacopoeia 28th Ed. 1982 p. 1311.
Facts & Comparisons 12/76 Product List for Antihist, Contg. Prep. Topical pp. 572-573.
Remington's Pharmaceutical Sciences 15th ed. 1975 pp. 1252-1253.
Chem. Abstracts 86(1):620c Antibacterial Activity of Ambodryl and Benadryl Jan. 3, 1977.
Chem Abstracts 86(11):66137g Antimicrobial Activity of Antihistaminic Drugs Mar. 14, 1977.
Chem. Abstracts 102(17):146020c In Vitro Activity of Ethanolamine- and Phenothiazine Derived and Aminoalkyl Antihistamines Against Some Selected Bacterial Strains 4/9/85.
Drug Evaluations 6th edition (American Medical Association) pp. 1503-1507.

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