Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-05-31
2011-05-31
Habte, Kahsay T (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S010000
Reexamination Certificate
active
07951800
ABSTRACT:
The present invention provides HCV polymerase inhibiting compounds having the formula (I):where R1is cyclobutyl-N(Ra)—, n is 1, 2, 3 or 4, and at least one R5is RaSO2N(Rj)alkyl-. In a non-limiting example, a compound of the present invention is N-[(3-{1-[(cyclobutyl)amino]-4-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl}-1,1-dioxo-1,4-dihydro-1λ6-thieno[2,3-e][1,2,4]thiadiazin-7-yl)methyl]methanesulfonamide. The present invention also features compositions comprising the compounds of the present invention or pharmaceutically acceptable salts, stereoisomers or tautomers thereof, and methods of using the same to treat or prevent HCV infection.
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Donner Pamela L.
Kempf Dale J.
Maring Clarence J.
Stoll Vincent S.
Wagner Rolf
Abbott Laboratories Inc.
Davis Bradley E.
Habte Kahsay T
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