Anti-infectious carbohydrates

Details Anti-infectious carbohydrates Anti-infectious carbohydrates

2002-09-25

2010-12-28

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S062000, C536S055200, C536S123100, C426S658000

Reexamination Certificate

active

07858595

ABSTRACT:
Neutral straight-chain or branched oligosaccharides for preventing the invasion and infection of mammal cells by pathogens and for fighting diseases caused by such pathogens are disclosed. Food, dietetic products and pharmaceutical agents containing oligosaccharides consist of a base unit of formula (I), and between 0 and 19 other units of formula (II), which are linked directly or indirectly to the base unit. Gal represents a galactose monosaccharide unit; Glc represents a glucose monosaccharide unit; HexNAc rpresents an N-acetylated galactosamine or glucosamine monosaccharide unit (GalNAc or GlcNAc); R independently represent a β 1-3 or β 1-6 glycosidic link to HexNAc monosaccharide of the next [Gal-HexNAc] unit (II), and on a terminal [Gal-HexNAc] unit, or R are not present; and a terminal [Gal-HexNAc] unit, wherein R represent a deoxyhexose radical, can have another deoxyhexose radical on the HexNAc monosaccharide unit.

REFERENCES:
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patent: 5294537 (1994-03-01), Batt
patent: 6045854 (2000-04-01), Prieto et al.
patent: 6146670 (2000-11-01), Prieto et al.
Gibson et al, “Regulatory Effects of Bifidobacteria on the Growth of Other Colonic Bacteria”, Journal of Applied Bacteriology, 1994, vol. 77, pp. 412-420.

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