Anti immune complex antibody for determining SLE, rheumatoid art

Details Anti immune complex antibody for determining SLE, rheumatoid art Anti immune complex antibody for determining SLE, rheumatoid art

1983-04-07

1985-10-01

Marantz, Sidney

Chemistry: analytical and immunological testing

For preexisting immune complex or auto-immune disease

260112R, 435 7, 435 68, 4351722, 436507, 436509, 436512, 436547, 436548, 935 93, 935110, G01N 3354

Patent

active

045446407

ABSTRACT:
An antibody is obtained by using as an antigen a complex of an antigen and the F(ab').sub.2 fragment of the human antibody of this antigen or an aggregate of the F(ab').sub.2 fragment of human immunoglobulin. This antibody reacts with an immune complex in a blood serum of a patient of systemic lupus erythematosus and with an immune complex in a blood serum of a patient of rheumatoid arthritis, and it does not react with an aggregated IgG. The amount of immune complex in a blood serum is easily and exactly determined by using this antibody.

REFERENCES:
patent: 4210622 (1980-07-01), Soothill
patent: 4283383 (1981-08-01), Masson
patent: 4332783 (1982-06-01), Pernice
patent: 4342566 (1982-08-01), Theofilopoulos
Chemical Abstracts, 88: 168279p (1978).

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