Chemistry: molecular biology and microbiology – Vector – per se
Patent
1995-03-01
1997-12-30
Loring, Susan A.
Chemistry: molecular biology and microbiology
Vector, per se
5303871, 5303873, 53038823, 5303881, C12N 1500, C07K 1600, C07K 1624, C12P 2108
Patent
active
057029466
ABSTRACT:
Anti-IL-8 monoclonal antibodies are described for use in diagnostic applications and in the treatment of inflammatory disorders such as inflammatory bowel disease and bacteria pneumonias.
REFERENCES:
patent: 4816567 (1989-03-01), Cabilly et al.
Boylan, A.M. et al., J Clin Invest, 89:1257-1267, Apr. 1992.
Broaddus, V.C. et al, Am. Rev Respir Dis, 146:825-830, 1992.
Neuberger, M.S. et al, Phil Trans. R. Soc. Londa, 317:425-432, 1986.
Cross et al., "Choice of Bacteria in Animal Models of Sepsis" Inf. & Immunity 61(7):2741-2747 (Jul. 1993).
Harris et al., "Therapeutic antibodies--the cloning of age" Tibtech 11:42-44 (Feb. 1993).
Hebert et al., "Interleukin-8: A Review" Cancer Investigation 11(6):743-750 (1993).
Ko et al., "A sensitive enzyme-linked immunosorbent assay for human interleukin-8" J. Immunol. Methods 149:227-235 (1992).
Mulligan et al., "Inhibition of Lung Inflammatory Reactions in Rats by an Anti-Human IL-8 Antibody" 150(12):5585-5595 (Jun. 15, 1993).
Sartor, R. Balfour, "Animal Models of Intestinal Inflammation--Relevance to Inflammatory Bowel Disease" Inflammatory Bowel Disease (Chapter 18), MacDermott et al., New York:Elsevier pp. 337-353 (1992).
Sekido et al., "Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8" Nature 365:654-657 (Oct. 14, 1993).
St. John et al., "Immunologic Therapy for ARDS, Septic Shock, and Multiple-Organ Failure" Chest 103:932-943 (1993).
Sticherling et al., "Immunohistochemical studies on NAP-1/IL-8 in contact eczema and atopic dermatitis" Arch. Dermatol. Res. 284:82-85 (1992).
Sticherling et al., "Production and Characterization of Monoclonal Antibodies Against the Novel Neutrophil Activating Peptide NAP/IL-8" J. Immunol. 143(5):1628-1634 (Sep. 1, 1989).
Wada et al. Journal of Experimental Medicine 180:1135-1140 (Sep. 1994).
Waldman, Thomas A., "Monoclonal Antibodies in Diagnosis and Therapy" Science 252:1657-1662 (Jun. 21, 1991).
Doerschuk Claire M.
Fong Sherman
Hebert Caroline Alice
Kim Kyung Jin
Leong Steven R.
Genentech Inc.
Loring Susan A.
Love Richard B.
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